CONservative TReatment of Appendicitis in Children – a randomised controlled Trial (Feasibility)


Hi everyone!

So I’m sure you are aware that this week the new trial for treating appendicitis commenced- very exciting!

Please find below a summary of what we need to know.


A clinical trial for children with uncomplicated acute appendicitis. Overall, we aim to see if children with appendicitis can be treated without an operation. In this trial we will be comparing treatment with antibiotics alone with appendicectomy.

Who is eligible?

Children age 4-15 years who have acute uncomplicated appendicitis.

What do I need to know?

We would like you to know the study is taking place so you are aware that we will be treating some children with antibiotics alone, instead of an operation. Also, we would like to ask you to try and avoid telling any child / family who may have appendicitis that the treatment for appendicitis is an operation. This is because it may be hard to encourage them to go into the trial if they have already heard a health professional tell them that they will need an operation.

Who will approach the child / family?

The clinical team looking after the child will do this supported by research nurses.

What do I need to do?

Just continue to provide the high quality care to these children that you always do. The clinical and research teams will take care of the rest.

Where can I find more information?

Please ask one of the research team or the local investigators who are: Mr Nigel Hall and Mr Mike Stanton.

Best wishes

Jo, Karen, Rhoda


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